Empirical Bayes Model Comparisons for Differential Methylation Analysis
نویسندگان
چکیده
منابع مشابه
Semi-Bayes and empirical Bayes adjustment methods for multiple comparisons.
Epidemiological studies often involve multiple comparisons, and may therefore report many "false positive" statistically significant findings simply because of the large number of statistical tests involved. Traditional methods ofadjustment for multiple comparisons, such as the Bonferroni method, may induce investigators to ignore potentially important findings, because they do not take account...
متن کاملEMPIRICAL BAYES ANALYSIS OF TWO-FACTOR EXPERIMENTS UNDER INVERSE GAUSSIAN MODEL
A two-factor experiment with interaction between factors wherein observations follow an Inverse Gaussian model is considered. Analysis of the experiment is approached via an empirical Bayes procedure. The conjugate family of prior distributions is considered. Bayes and empirical Bayes estimators are derived. Application of the procedure is illustrated on a data set, which has previously been an...
متن کاملstatistical inference via empirical bayes approach for stationary and dynamic contingency tables
چکیده ندارد.
15 صفحه اولEmpirical Bayes Estimators with Uncertainty Measures for NEF-QVF Populations
The paper proposes empirical Bayes (EB) estimators for simultaneous estimation of means in the natural exponential family (NEF) with quadratic variance functions (QVF) models. Morris (1982, 1983a) characterized the NEF-QVF distributions which include among others the binomial, Poisson and normal distributions. In addition to the EB estimators, we provide approximations to the MSE’s of t...
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ژورنال
عنوان ژورنال: Comparative and Functional Genomics
سال: 2012
ISSN: 1531-6912,1532-6268
DOI: 10.1155/2012/376706